The principal cytochrome P450 isoenzyme included appears to generally be CYP2E1, with CYP1A2 and CYP3A4 as more pathways. Close to eighty five% of an oral dose seems while in the urine in 24 hours of administration, most as being the glucuronide conjugate, with modest quantities of other conjugates and unchanged drug (see OVERDOSAGE) for toxicity i